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ADHD RESEARCH UPDATE - Vol. 14, December, 1998
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In this issue...

* NIH Conference on the diagnosis and treatment of ADHD

* Alternative treatments for ADHD: What is their scientific status?

* Report of an effective new medication for adults

* Language difficulties in children with ADHD

READER QUESTIONS

If ADHD is a brain disorder, how can it truly be treated without medication?

Are there different levels of ADHD and is behavioral treatment only appropriate for milder cases?


* NIH Consensus Conference on ADHD

The National Institute of Health recently convened a conference on ADHD that was attended by leading authorities on this disorder from multiple disciplines. The purpose of this conference was to generate a widely shared agreement about the central facts about the diagnosis and treatment of ADHD based on the current research literature. Important directions for future research were also discussed.

The findings to come out of this conference represent the current state of knowledge in the field as agreed to by multiple experts. I will try to highlight the major conclusions reached by panel for the six different questions that they addressed. (Note: The information below is based on a Draft version of the consensus statement, and it is possible that the final version will contain modifications.)

What is the Scientific Evidence to Support ADHD as a Disorder?

As you may know, there are still many individuals who doubt that ADHD even exists. Even some health care professionals continue to regard ADHD as an excuse for poorly behaved child with parents who do not know how to discipline. Because of this continuing concern, the panel first considered evidence that supports the validity of ADHD as a disorder.

The panel concluded that there is validity in the diagnosis of ADHD, and that the diagnosis can be made reliably using well tested diagnostic interview methods. Evidence supporting the validity of ADHD includes the predictable course of ADHD over time, studies in different cultures that reveal similar characteristics for the disorder, and the fact that ADHD has been shown to have a strong genetic component.

Several cautions were also noted, however. As yet, an independent, valid test for ADHD does not exist. This means that there is not single procedure or "objective" test that can be routinely used to determine whether or not a child or adult has ADHD, and that a careful evaluation relying on information collected from multiple sources is still required. Furthermore, although prior research does indicate differences in brain functioning between individuals with and without ADHD, there is no conclusive evidence that ADHD is caused by a brain malfunction. (Note: There is certainly evidence which strongly suggests that this is the case, however. Scientists tend to have a very high standard for what constitutes "conclusive evidence" for something. We know, for example, that important differences in brain activity have been found for people with ADHD. This does not necessarily mean, however, that such differences are the actual cause of the disorder. I think this is probably what the panel had in mind.)

The consensus statement drafted by the panel also noted difficulties in differentiating ADHD from other behavioral problems, and the need to develop more reliable methods for doing this. It is also the case that the reported rate of ADHD in some countries is much lower than in the US. This indicates the need for better study of ADHD in different populations and better definition of the disorder.

Finally, it was noted that all formal diagnostic criteria for ADHD were designed for diagnosing young children. Diagnostic criteria that are sensitive to changes in how ADHD may appear in older children and adults need to be developed. If you look at what the formal diagnostic criteria for ADHD you will see that this is clearly true. Developing diagnostic criteria that are more appropriate for older individuals is clearly needed.

What is the Impact of ADHD on Individuals, Families and Society?

The statement issued by the panel notes the wide ranging effect that ADHD has on children, their families, and society. Many children with ADHD experience peer rejection and engage in a broad array of disruptive behaviors. They are more prone to accidents than other children and are at increased risk for developing serious behavioral disturbances such as conduct disorder. For many children, the adverse impact of ADHD continues into adulthood.
 

    Research clearly shows that families who have children with ADHD experience increased levels of parental
    frustration, marital discord, and divorce. The costs of caring for a child with ADHD can be substantial and
    represents a serious burden for many families because these costs are often not covered by health insurance.

    This clear description of the adverse impact that ADHD can have on parents and families is important. In many
    cases, even when a child is getting treatment, little or no treatment/ support is provided to parents who are
    contending with the frustrations and difficulties that having a child with ADHD can cause. Research has shown that
    this can take an important toll on parents' own sense of well being.

    For those of you who may be experiencing such stress, it is important to know that this is a frequent complication
    of the disorder and getting assistance to cope with such stress, perhaps by participating in a parent support group
    can be extremely helpful. Many physicians who treat ADHD fail to consider the impact on other family members
    and do not encourage parents to seek out the assistance that they may also need.

    Although methodological problems make it hard to define the precise costs of ADHD to society, it is clear that they
    are huge. Additional public school expenditures on behalf of students with ADHD exceeded $3 billion in 1995.
    This is but a fraction of the dollars that are spent each year on problems that are either directly or indirectly related
    to ADHD.

    What are Effective Treatments for ADHD?

    The panel notes that available research data clearly supports the efficacy of stimulant medication treatment and
    certain types of behavioral treatment on the core symptoms of ADHD (see the prior issue of ADHD RESEARCH
    UPDATE for a more extended discussion of empirically supported behavioral treatments).

    There are a number of important questions and caveats that were also raised, however.

    * Studies of treatment efficacy have been short term - generally 3 months or less.

    Although it is hard to believe, there are no long term studies testing stimulants or psychosocial treatments that last
    several years. There is thus no conclusive information on the long term outcomes of medication-treated children in
    terms of educational and occupational achievements, or other important areas of social functioning. It is important
    to note, however, that several studies have been conducted in which children taking stimulant medication were
    followed for durations of 12-24 months. These studies indicate that when prescribed properly, and when children
    are carefully followed, the beneficial effects of medication treatment seem to persist.

    * Almost all treatment studies have been conducted on children who show both inattentive and
    hyperactive/impulsive symptoms.

    Basically, there is very little treatment data on children who show attention problems only without the hyperactive/
    impulsive symptoms (i.e. children who are diagnosed in the current system as ADHD, Predominantly Inattentive
    Type). This is particularly important because this subgroup of children with ADHD may contain a higher
    percentage of girls. (In my own experience, I have certainly found that stimulant medications are also effective for
    children with the inattentive type of ADHD. Specific research on this population is needed, however.)

    * There is no conclusive data on treatment of ADHD in adolescents and adults.

    Most of the treatment research has been conducted with school age children, and the data base looking at
    adolescents and adults is much smaller. As you have seen in prior issues of ADHD RESEARCH UPDATE,
    however, studies examining the efficacy of stimulant medication treatment in adolescents does indicate that it is
    effective, at least over the short term. More work on medical and non-medical treatments for older individuals
    with ADHD is clearly needed, however.

    Preliminary evidence from a large scale, longer term treatment study that promises to fill in important gaps in our
    knowledge was also discussed. It was noted that medication treatment that includes using systematic and intensive
    monitoring methods over approximately one year may be superior to an intensive set of behavioral treatments on
    core ADHD symptoms (i.e. inattention, hyperactivity/impulsivity, aggression).

    (Unfortunately, in the real world, careful monitoring of a child's response to medication over time is rarely done.
    The ADHD Monitoring System that you should have received as a bonus with your subscription provides a
    reasonable method for doing this and I hope that you are using it. If for any reason you did not receive this when
    you subscribed, please let me know so I can send it to you.)

    Data from the large, ongoing treatment study noted above is suggesting that the combination of medication and
    behavioral treatment may result in improved social skills for children with ADHD. In addition, parents and
    teachers judged this combined treatment more favorably. An important potential advantage for combined treatment
    is the possibility of improving a child's functioning with a reduced dose of stimulants, although existing data do not
    permit any firm conclusions about this.

    The panel also noted the long history of other treatments for ADHD including dietary interventions, herbal
    treatments, various vitamin or mineral regimens, biofeedback, perceptual stimulation, etc. Their conclusion is that
    the empirical evidence pertaining to these interventions is generally sparse, and that the efficacy for all these other
    treatments still remains to be established. It was stated, however, that some of the dietary elimination strategies
    (i.e. eliminating from a child's diet certain foods or additives believed to exacerbate ADHD symptoms) have
    shown some intriguing results that suggest future research in this area should be pursued. (Note: This is the most
    positive statement on dietary interventions from a scientific panel that I have seen. I will be looking for research in
    this area to present in future issues of ADHD RESEARCH UPDATE.)

    What are the Risks of the use of Stimulant Medication and Other Treatments?

    The panel provides a very cautious statement on the risks associated with the long term use of stimulant
    medications.

    "Although little information concerning the long-term effects of psychostimulants, there is no conclusive evidence
    that careful therapeutic use is harmful. When adverse drug reactions do occur they are usually related to dose.
    Effects associated with moderate doses may include decreased appetite and insomnia. These effects occur early in
    treatment and may decrease with continued dosing. There may be negative effects on growth rate, but ultimate
    height appears not to be effected."

    How are we supposed to interpret this statement and what does it really mean about the long term safety of
    treatment with stimulant medication? I find the statement to be distressingly vague, although it is as strong a
    statement as can be made based on currently available evidence. Basically, the available data on the long term
    effects of stimulant medication does not permit one to conclude that there is no possibility of adverse health effects,
    but there is also no evidence that they are harmful. It would be nice to be able to make a stronger conclusion than
    this, and given how long stimulant medications have been prescribed, it is surprising that more long term data is
    not available. Clearly, however, there is not sufficient concern about safety among the panel for them to suggest
    that long term use is not advisable. Overall, the conclusion seems to be that the ratio of potential benefits to
    potential risks is highly favorable. It should be noted, however, that although this may have been the consensus
    view, not everyone agreed with this conclusion.

    Several important concerns were raised, however. The panel stated that psychostimulants do have abuse potential
    and that very high doses can result in central nervous system damage, cardiovascular damage, and hypertension.
    Unfortunately, what constitutes a "very high" dose was not defined, although it is my understanding that this is
    certainly above what should be required to produce a therapeutic response in most children. If you are concerned
    about your own child's dosage, please be sure to discuss your concerns with your child's doctor.

    The panel noted that the degree of assessment and follow up by primary care physicians who prescribe stimulant
    medication varies significantly. In many cases, appropriate procedures for these important functions are just not
    used. My own opinion about this is that this results in many children taking medication who may derive no real
    benefit from it, or, who are maintained on a less than optimal dose.

    The panel suggested that little is currently known about the illicit use of stimulant medication, but that there is little
    evidence that current levels of availability have had a substantial effect on abuse. The need to be vigilant in
    monitoring the use and possible abuse among high school students was emphasized.

    What are the Existing Diagnostic and Treatment Practices, and What are the Barriers to Appropriate
    Identification, Evaluation, and Intervention?

    The panel was actually quite critical about the way ADHD is often diagnosed. They noted that there is wide
    variation in the frequency of diagnosis made by different types of providers (e.g. pediatricians, family physicians,
    psychologists, neurologists, psychiatrists), and that diagnoses are often made in an inconsistent manner. As a result,
    many children are misdiagnosed - either being identified as having ADHD when they do not or not being properly
    identified when they do.

    The panel noted that some practitioners do not use any standardized procedures for making the diagnosis - either
    structured interviews, or standardized behavior rating scales. They were particularly concerned about how often
    the diagnosis is made without the practitioner obtaining any direct information from the child's teacher. It was
    noted that pediatricians, family physicians, and psychiatrists tend to rely on parent input only rather than also
    collecting information from the child's school and teacher. (For more detailed information on what I think is a
    reasonable approach to evaluating a child for ADHD, click here.)

    Just as the diagnosis is often made without direct input from the child's school, the panel also noted that there is
    often poor communication concerning a child's response to treatment. They note that follow up is often "inadequate
    and fragmented", and stress the importance of careful monitoring to determine how treatment is working and to
    detect any adverse effects of treatment. It is really a shame how infrequently this is done - most children are simply
    put on medication with little or no systematic procedure in place to determine how effective the medication is
    being, and what difficulties may still need to be addressed via other means even if the medication is helping with
    the core ADHD symptoms.

    The panel implied that the quality of the evaluation a child receives and the type of treatment recommended may
    depend on the type of provider doing the evaluation. They stated that primary care practitioners (e.g. pediatricians
    and family physicians) are less likely to recognize the other difficulties that often go along with ADHD (e.g.
    behavioral, social, emotional, and academic problems). This can result in a child failing to receive the
    comprehensive treatment approach that may be necessary. They also mention data that indicates family
    practitioners are more likely to prescribe stimulant medication than other types of physicians.

    My own experience certainly indicates that these concerns are valid ones. There are, of course, many pediatricians
    and family physicians who do an absolutely outstanding job of evaluating children for behavioral disorders such as
    ADHD and who make certain that all necessary and appropriate forms of treatment are considered. I hope that you
    have been fortunate in being able to find such a person.

    In regards to barriers to appropriate identification, evaluation, and treatment, the primary one described is the lack
    of adequate insurance coverage. Many health insurance policies simply do not provide sufficient coverage for an
    adequate evaluation and families often can not afford the out of pocket expenses that are required.

    A perfect example of this is that few if any plans will reimburse a provider for visiting a child's school to observe
    the child in the classroom and to consult directly with his or her teacher. In many cases, this can be one of the most
    important things for the therapist to do, but there is no insurance coverage for this and parents can not afford to bear
    the expense.

    What are the Directions for Future Research?

    A number of important research questions and areas were identified including:

    Developing age appropriate diagnostic criteria for adolescents and adults;

    Studies of the inattentive type of ADHD, especially since girls may be overly represented in this subtype;

    Studies of long term treatment with a focus on the risks and benefits of long term treatment with stimulant
    medications;

    Studies on the effects of different educational/instructional methods on the academic achievement of children
    with ADHD;

    Studies to determine whether the combination of stimulants and behavioral treatments can improve functioning
    with a reduced dose of stimulants;

    Studies to determine the risks and benefits of treating children younger than 5 with stimulants;

    The panel also emphasized that work needs to be done in the following areas:

    Developing a more consistent set of diagnostic procedures and practice guidelines;

    Model projects should be developed to demonstrate methods of training teachers to recognize and provide
    appropriate special programs for children with ADHD;

    Developing and incorporating classroom strategies that effectively serve a greater variety of students;

    Determining the extent to which individuals with ADHD are being served in post secondary education (i.e.
    college), how successful they are being, and what types of accommodations are necessary to help enhance their
    success.

    I hope the above summary of this important conference provides you with a good appreciation for the current state
    of knowledge and practice in the field. (Remember, this is a "draft" statement, and it is certainly possible that
    changes will be made for the final version, although I would not expect any major revisions.) As is evident, there
    are some important gaps in our knowledge of how to best evaluate and treat ADHD, and the gaps between what
    should be done and what is often done is even more concerning. For the complete text of the consensus statement
    drafted by the panel click here
 
 

    The Scientific Status of Alternative Treatments for ADHD
 

    At the NIH Consensus Conference noted above, Dr. Eugene Arnold, an emeritus professor of Psychiatry from the
    University of Ohio, presented a very interesting talk in which he summarized the current scientific evidence for a
    variety of alternative treatments for ADHD. I know this is an area that many people have interest in, so I wanted to
    present his paper in some detail.

    Based on his review of the existing research literature, Dr. Arnold rated the alternative treatments presented on a
    0-6 scale. It is important to understand this scale before presenting the treatments. (Note that this is one person's
    opinion based on the existing data - other experts could certainly disagree). The scale he used is presented below:

    0 - no supporting evidence and not worth considering further;

    1 - based on a reasonable idea but no data available; These would be treatments not yet subjected to any real
    scientific study;

    2 - Promising pilot data but no careful trial; These would be treatments where very preliminary work appears
    promising but where the treatment approach is in the very early stages of investigation.

    3 - Supporting evidence beyond the pilot data stage but carefully controlled studies lacking; This would apply to
    treatments where only "open" trials and not double-blind controlled trials have been done.

    (Let me briefly review the difference between an "open" trial and a double-blind trial because this is a very
    important distinction. Say you are testing the effect of a new medication on ADHD. In an open trial, you would just
    give the medication to the child, and then collect data on whether the child improved from either parents or
    teachers. The child, the child's parents, and the child's teacher would all know that the child was trying a new
    medication.

    In a double-blind trial, the child would receive the new medicine for a period of time and a placebo for a period of
    time. Neither the child, parents, nor teacher would know when medication or placebo was being received. The
    same type of outcome data as above would be collected - during both the medication period and the placebo
    period.

    The latter is considered to be a much more rigorous test of a new treatment - whether it be a new medication, a
    dietary intervention, or some other alternative - because it enables researchers to determine whether any changes
    reported/observed are above and beyond what can be attributed to a placebo effect. In an open trial, you can not be
    certain that any changes reported are actually the result of the treatment, as opposed to placebo effects alone. It is
    also the case that it is very hard for anyone to provide objective ratings of a child's behavior when they know that a
    new treatment is being tried. For these reasons, "open" trials - even if they yield very positive results - are
    considered to be only preliminary evidence in support of any new treatment.)

    4 - One significant double-blind controlled trial that requires replication; (Note: Replicating a favorable
    double-blind study is very important. The literature is full of initially promising reports that could not be
    replicated.)

    5 - Convincing double-blind controlled evidence but needs further refinement for clinical application. This rating
    would be given to treatments where replicated double-blind trials are available, but where it is not completely
    clear who the treatment is best suited for. For example, a treatment may be known to help children with ADHD, but
    it may be effective for only a minority of the ADHD population and the specific subgroup it is effective for is not
    clearly defined.

    6 - A well established treatment for the appropriate subgroup.

    Of the numerous alternative treatments reviewed by Dr. Arnold, no treatments received a rating of 6 and only one -
    dietary treatments that involve placing children on diets that eliminate their exposure to certain foods or food
    additives that they have allergic reactions to. Dr. Arnold concludes that there is convincing scientific evidence that
    some children who display symptoms of ADHD can derive significant benefits from appropriate dietary
    treatments. The important task, as he sees it, is to determine what percentage of the ADHD population dietary
    responders constitute (i.e. is it a very small minority of a larger proportion; the general view is that the percentage
    is quite small) and to better identify the child who is likely to respond to dietary treatment. Preliminary evidence
    suggests that the type of child most likely to respond is a preschooler with a history of prominent irritability and
    sleep disturbance. Dietary interventions are also more likely to be helpful if there is a family history of migraines,
    or if a parent can give a definite example of a food/behavior change connection.

    There were two alternative treatments for which a rating of 4 was assigned (i.e. a convincing double blind trial
    that requires replication). This treatment involves relaxation training using a type of biofeedback procedure (i.e.
    EMG biofeedback). There is some preliminary evidence that relaxation training does result in reductions in ADHD
    symptoms (recall a recent article reviewed in ADHD RESEARCH UPDATE about the possible benefits of
    massage) and Dr. Arnold believes that this treatment approach warrants further investigation. It is not clear what
    the magnitude of the benefits are nor how long they would be expected to last.

    The second treatment for which some positive data from controlled, double-blind trials exist is "deleading" (i.e.
    reducing lead levels in the bloodstream). Positive effects are restricted to those children who have elevated blood
    lead levels to begin with; for such children, Dr. Arnold argues that deleading would be the treatment of choice. To
    how low a blood lead level this treatment should extend is currently unknown.

    Several alternative treatments received ratings of "3", indicating promising results from initial studies, but for
    which the necessary double-blind controlled studies are lacking. Several studies have found that essential fatty
    acids tend to be lower in children with ADHD, and some preliminary data suggests that supplementing fatty acids
    in children with ADHD who have been shown to have low levels of these substances may result in behavioral
    improvement. Controlled trials of fatty acid supplementation should be pursued, although one would expect any
    beneficial effect to be restricted to those children with ADHD who are first shown to be deficient in their levels of
    these substances.

    Promising data from open trials of providing glyconutritional supplements (glyconutritional contain basic
    saccharides necessary for cell communication and formation of glycoproteins and lipids) have also been obtained.
    These results are from only 2 studies, however, with small sample sizes. Once again, placebo controlled trials are
    necessary.

    Promising initial results using several types of mineral supplements have also been reported. Iron supplementation
    has been associated with improvements in parent behavior ratings for ADHD boys, although no comparable
    improvement in teacher ratings was found. Magnesium supplementation has also yielded some promising
    preliminary results for children with ADHD who were also none to be deficient in magnesium. No double blind
    trials of either type of supplementation have been conducted.

    What about herbal treatments, an approach that is frequently touted? Two open trial studies using a "Chinese herbal
    cocktail" have reported extremely positive results, including the complete disappearance of all symptoms in 23 of
    80 subjects with no recurrence for 6 months, and improvement reported in 90% of participants. Careful, controlled
    trials of Chinese herbal treatments are certainly warranted. (Interestingly, Dr. Arnold could not find any systematic
    data for using pycnogenol for treating ADHD, even though this is widely marketed via the Internet and other
    vehicles.)

    Other treatments for which encouraging preliminary support has been reported include biofeedback, meditation,
    and some forms of perceptual stimulation and training. Controlled trials of all these approaches are lacking,
    however, and research on the latter two approaches has not been published in over 10 years.

    A number of alternative treatments were assigned ratings of 0 by Dr. Arnold, indicating that he views them as
    being not worth pursuing. Among these treatments are: eliminating sugar from children's diets, vitamin
    supplementation, amino acid supplementation, and hypnosis.

    There would seem to be several general conclusions that can be drawn from Dr. Arnold's excellent review of
    alternative treatments for ADHD? First, in contrast to the more standard treatments of stimulant medication and
    behavioral therapy, there are no alternative treatments for which comparable empirical support exists. Thus, there
    is really no alternative treatment that one could responsibly recommend prior to trying more standard treatments
    (exceptions may be deleading for children with high blood lead levels and thyroid treatment for children with
    known thyroid dysfunction.)

    Second, there are a number of promising alternative approaches that would be reasonable to consider if more
    standard treatments are not effective. Although the necessary data to support the more routine use of these
    alternatives does not yet exist, one hopes that the required double blind studies that provide support for these
    approaches will soon be available. Given some of the encouraging initial results reported for several approaches,
    it is somewhat surprising that more work in these areas has not been conducted.

    Finally, it should be noted that several alternative treatments reviewed, if they are clearly demonstrated to be
    effective, are likely to apply to only a subgroup of the ADHD population. For example, it would not make sense to
    provide nutritional or mineral supplementation to a child who is not deficient in either area to begin with.
 

    * Tomoxetine: Helpful new medication for adults with ADHD

    This article appeared in the May, 1998 issue of the American Journal of Psychiatry (pages 693-695) and reports on
    a study testing the effectiveness of Tomoxetine for treating ADHD in adults.

    Participants in the study were 22 adults with clear diagnoses of ADHD. During a 3 week trial, participants
    received both Tomoxetine and a placebo, and a variety of behavioral and laboratory measures of attention an
    impulsivity were collected. The average dose of the medication was 76 mg/day and few participants experienced
    any adverse side effects.

    During the placebo condition only 2 of 21 participants showed any improvement, compared to 11 of 21 who
    showed significant improvement when receiving Tomoxetine.

    Although these results are regarded as preliminary by the authors, they are promising nonetheless, and follow up
    research on this medication using a larger sample and a more extended treatment period is being planned. For
    adults struggling with ADHD symptoms, this may prove to be an important treatment alternative if other
    medications are not successful.
 

    * Language Difficulties in Children with ADHD

    This study appeared in the October 1998 issue of the Journal of Child Neurology (pages 493-497). The authors of
    this paper call attention to the frequent presence of language difficulties in children with ADHD - an important
    problem that is often overlooked.

    From an initial sample of 3208 children who were screened for ADHD, just over 5% were identified as having
    ADHD. These children, along with a randomly selected sample of the non- ADHD children, were then given IQ
    tests and language evaluations. Among the children with ADHD, 45% were identified as having language
    difficulties, and this occurred more often in girls than in boys. The percentage of children with language problems
    was much higher, of course, than for children without ADHD. In fact, children's performance on the language
    evaluation was more discrepant for the ADHD and non-ADHD children than was their performance on a routine
    IQ test. This is important because the authors note that the language difficulties for many children with ADHD were
    not reflected in their IQ test results.

    In discussing these results, the authors indicate that undiagnosed, and hence, untreated language difficulties may
    contribute substantially to the academic difficulties experienced by many children with ADHD. They argue,
    therefore, that language evaluations should be part of the routine assessment of children with ADHD.

    This is the first study that I have seen of this issue, but it is a well conducted study and the concern it raises about
    unaddressed language problems in children with ADHD is certainly an important one. If you have concerns about
    possible language difficulties in your child that may be contributing to difficulties with academic functioning,
    pursuing an evaluation of your child's language functioning should be considered. This can generally be obtained at
    no charge through the public school system.
 

    - READER QUESTIONS -

    If ADHD is a brain disorder, how can it truly be treated without medication?

    First, as noted above, the conclusion of the NIH Consensus Panel is that evidence that ADHD is caused by a brain
    malfunction does not yet exist. This strikes many as a very conservative statement, given the results of several
    studies which have documented differences in certain aspects of brain functioning between individuals with and
    without ADHD. I think the panel took this position, however, because the fact that finding such differences does not
    necessarily mean that they are the actual "cause" of ADHD. For example, these differences could possibly be the
    result of having ADHD rather than the cause, or may be associated with some other factor that actually "causes" the
    disorder.

    Even if ADHD is eventually shown to be clearly and unambiguously caused by differences in brain function,
    however, this does not necessarily mean that medication must be the only treatment. For example, many cases of
    depression are known to be associated with changes in brain chemistry, and yet psychotherapy without medication
    is clearly an effective treatment for many individuals who suffer from depression. Psychosocial treatments can
    actually alter brain chemistry in ways similar to medication induced changes, as potentially, can other substances
    besides stimulant medication. Thus, there is no a priori reason why medication would need to be the only effective
    treatment for ADHD, or any other psychiatric disorder for that matter, regardless of whether a clear biological
    cause has been identified.
 

    Are there different levels of ADHD and are behavioral treatments alone appropriate for mild forms of
    ADHD only?

    There are definitely different levels of severity of ADHD. For some children, even though they meet the criteria for
    the diagnosis, their symptoms are relatively mild. Other children , in contrast, display symptoms of much greater
    intensity and are significantly more difficult to manage.

    It is also important to recognize that the severity of a child's symptoms can vary significantly over time, and even at
    the same point in time across different settings. Thus, some children experience a diminishing of their symptoms as
    they grow older - many times to the point where the symptoms no longer cause significant impairment and the child
    - who may now be a teen or young adult - no longer would be diagnosed with ADHD. (At this point, it is not
    possible to predict, as far as I know, who this will occur for and who it will not.)

    A child's symptoms can also show varying levels of severity across different settings. For example, it is not
    uncommon for a child's symptoms to be much more evident and impairing at school then they are at home. Even
    within the school setting, a child's symptoms can even be more severe with one teacher than another because of
    differences in how the two classrooms may be structured and differences in teaching style. This is why it is so
    important for parents to work hard to try and make sure their child gets a teacher each year who works well with
    children who have ADHD. In my own experience, I have seen many times what an enormous difference having the
    right teacher can make for the success of a child's school year.

    In relation to whether behavioral treatments are appropriate for children with "mild" case of ADHD only, I am not
    aware of any studies that have looked specifically at the success rate for behavioral treatments in relation to the
    severity of a child's symptoms. I believe the general view among the medical and mental health professions is that
    the more severe a child's symptoms, the more likely it is that medication will need to be a part of the child's
    treatment. Of course, the more severe a child's symptoms, the more likely it is that other forms of intervention -
    including behavioral treatments - will play an important role in the child's overall treatment plan.
 

    That's all for this month...

    I hope you enjoyed this issue of ADHD RESEARCH UPDATE and found it to be informative.

    For those of you who have been kind enough to include a link to my web site on your own site, I want to let you
    know that my URL has changed. My new address is: www.helpforadd.com. If you would change the linking
    information when you have the time I would appreciate it. I will finally - I hope - be getting my own links page up
    later this month when I have some time off, so please let me know if you would like to be included.

    As always, I would appreciate your letting others know about ADHD RESEARCH UPDATE who you think might
    be interested. If people send a request for sample issues to addhelp@mindspring.com I will be delighted to send
    them several issues to review.

    Take care.
 

    Sincerely,
 

    David Rabiner, Ph.D.
    Licensed Psychologist

    P.S. I continue to offer consultation via telephone to subscribers who would like to discuss their questions and
    concerns about their child's development in detail. If you are interested in learning more about this service, and
    whether it may be helpful for you, please get in touch.

    copyright ADHD RESEARCH UPDATE, 1998